User:Gabriel Marceau: Difference between revisions
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CHU Sainte-Justine<br> | CHU Sainte-Justine<br> | ||
Laboratory of pediatric liver diseases, Dr Fernando Alvarez<br> | |||
3175 chemin de la Côte-Ste-Catherine<br> | 3175 chemin de la Côte-Ste-Catherine<br> | ||
Montreal, Québec<br> | Montreal, Québec<br> | ||
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=== Techniques === | === Techniques === | ||
<blockquote> | <blockquote> | ||
* | *Histology | ||
**Cryostat ultra thin sections | |||
**Hematoxylin and eosin staining | |||
**Luxol fast blue staining | |||
**Immunohistochemistry labelling antibodies / DAB | |||
*Molecular biology | |||
**Molecular cloning | |||
**Protein production in bacteria | |||
**Protein purification (antibodies) | |||
*Immunology | |||
**Flow cytometry | |||
**ELISA | |||
**Proliferation assays | |||
*Virology | |||
**Amplification | |||
**Plaque forming assay titration | |||
**Detection by polymerase chain reaction (PCR) | |||
*Cell culture (primary and cell lines) | |||
**Mouse spleen cells | |||
**Liver infiltrating lymph nodes | |||
**Purification and culture of mouse T lymphocytes | |||
***Spleen | |||
***Lymph nodes | |||
***Liver | |||
***Central nervous system | |||
*Animal experimentation | |||
**Mouse | |||
</blockquote> | </blockquote> | ||
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<blockquote> | <blockquote> | ||
*Travel Award, [http://www.neuroinflammation.com NeuroInflammation Training Program (IRSC/FRSQ)], 2008 | *Travel Award, [http://www.neuroinflammation.com NeuroInflammation Training Program (IRSC/FRSQ)], 2008 | ||
*Travel Award, [http://www.fondation-afrappier.qc.ca Fondation Armand-Frappier], 2007 | |||
*Travel Award, [http://www.neuroinflammation.com NeuroInflammation Training Program (IRSC/FRSQ)], 2007 | *Travel Award, [http://www.neuroinflammation.com NeuroInflammation Training Program (IRSC/FRSQ)], 2007 | ||
*Award, [http://www.mssociety.ca Multiple Sclerosis Society of Canada], 2007-2008 | *Award, [http://www.mssociety.ca Multiple Sclerosis Society of Canada], 2007-2008 | ||
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=== Master's thesis === | === Master's thesis === | ||
<blockquote> | <blockquote> | ||
*'''Gabriel Marceau'''. 2003. [Infection | *'''Gabriel Marceau'''. 2003. [Infection by hepatitis C virus and autoantibodies against cytochrome P450IID6: role of molecular mimicry]-French. [http://www.umontreal.ca Université de Montréal]. | ||
</blockquote> | </blockquote> | ||
=== Doctoral thesis === | === Doctoral thesis === | ||
<blockquote> | <blockquote> | ||
*'''Gabriel Marceau'''. 2010. [ | *'''Gabriel Marceau'''. 2010. [Transient immunosuppression in a mouse model of multiple sclerosis]-French. [http://www.iaf.inrs.ca INRS - Institut Armand-Frappier]. | ||
</blockquote> | </blockquote> | ||
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<blockquote> | <blockquote> | ||
*Igal Ifergan, Hania Kebir, '''Gabriel Marceau''', Monique Bernard, Pierre Talbot, Nathalie Arbour and Alexandre Prat. VLA-4-Dependent Recruitment of Effector Memory CD8+ T Lymphocytes into the Central Nervous System. FOCIS2009 June 11-14, 2009. San Francisco, CA, USA. Clin Immunol, 131: S11 (S1), 2009. | *Igal Ifergan, Hania Kebir, '''Gabriel Marceau''', Monique Bernard, Pierre Talbot, Nathalie Arbour and Alexandre Prat. VLA-4-Dependent Recruitment of Effector Memory CD8+ T Lymphocytes into the Central Nervous System. FOCIS2009 June 11-14, 2009. San Francisco, CA, USA. Clin Immunol, 131: S11 (S1), 2009. | ||
*'''Gabriel Marceau''' and Pierre Talbot. Immunomodulation by a neurovirulent coronavirus. 57th Annual Meeting of the Canadian Society for Microbiologists 17-20 | *'''Gabriel Marceau''' and Pierre Talbot. Immunomodulation by a neurovirulent coronavirus. 57th Annual Meeting of the Canadian Society for Microbiologists June 17-20, 2007. Université Laval, Québec, Canada. | ||
*'''Gabriel Marceau''' et Pierre Talbot. [Immunomodulation | *'''Gabriel Marceau''' et Pierre Talbot. [Immunomodulation by a neurovirulent coronavirus]-French. May 18, 2006. Colloque – Dialogues entre le système nerveux central et le système immunitaire. 74ème Congrès de l’ACFAS: Le savoir trame de la modernité du 15 au 19 mai 2006. Université McGill, Montréal, Canada. | ||
*'''Gabriel Marceau''' and Pierre Talbot. Immunomodulation by a neurovirulent murine coronavirus. | *'''Gabriel Marceau''' and Pierre Talbot. Immunomodulation by a neurovirulent murine coronavirus. Mai 12, 2006. 1st Annual Neuroinflammation Symposium. Douglas Hospital, Montréal, Canada. | ||
*'''Gabriel Marceau''', Pascal Lapierre, Hugo Soudeyns et Fernando Alvarez. [Infection | *'''Gabriel Marceau''', Pascal Lapierre, Hugo Soudeyns et Fernando Alvarez. [Infection by hepatitis C virus and autoantibodies against cytochrome P450IID6: role of molecular mimicry]-French. November 6-8, 2003. Congrès INRS-Institut Armand-Frappier 2003. Manoir du Lac Delage, Stoneham, Canada. | ||
*Kathie Béland, Pascal Lapierre, '''Gabriel Marceau''' and Fernando Alvarez. Anti-LC1 autoantibodies in patients with chronic hepatitis C virus infection. 2-5 | *Kathie Béland, Pascal Lapierre, '''Gabriel Marceau''' and Fernando Alvarez. Anti-LC1 autoantibodies in patients with chronic hepatitis C virus infection. October 2-5, 2003. North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) 16th Annual meeting. Hotel Fairmont Queen Elisabeth, Montréal, Canada. JPGN, 37: 393 (A211), 2003. | ||
*'''Gabriel Marceau''', Pascal Lapierre, Hugo Soudeyns et Fernando Alvarez. [Infection | *'''Gabriel Marceau''', Pascal Lapierre, Hugo Soudeyns et Fernando Alvarez. [Infection by hepatitis C virus and autoantibodies against cytochrome P450IID6: role of molecular mimicry]-French. June 6, 2003. XVIIIème congrès annuel de la recherche des étudiants gradués et post-gradués. Centre de recherche de l’Hôpital Ste-Justine, Montréal, Canada. | ||
</blockquote> | </blockquote> | ||
=== Posters === | === Posters === | ||
<blockquote> | <blockquote> | ||
*'''Gabriel Marceau''', Hélène Jacomy, Marc Desforges, Claude Daniel and Pierre J. Talbot. Transient immunosuppression by a neurovirulent coronavirus in an animal model of multiple sclerosis. June 22-27 2008. XIth International Nidovirus Symposium. St. Catherine’s College Oxford, UK. | *'''Gabriel Marceau''', Hélène Jacomy, Marc Desforges, Claude Daniel and Pierre J. Talbot. Transient immunosuppression by a neurovirulent coronavirus in an animal model of multiple sclerosis. June 22-27, 2008. XIth International Nidovirus Symposium. St. Catherine’s College Oxford, UK. | ||
*'''Gabriel Marceau''' and Pierre J. Talbot. Immunomodulation by a neurovirulent murine coronavirus. December 7- | *'''Gabriel Marceau''' and Pierre J. Talbot. Immunomodulation by a neurovirulent murine coronavirus. December 7-10 2007. EndMS.ca. Fairmont Banffsprings, Banff, Canada. | ||
*'''Gabriel Marceau''' and Pierre Talbot. Immunomodulation by a neurovirulent murine coronavirus. 11-12 | *'''Gabriel Marceau''' and Pierre Talbot. Immunomodulation by a neurovirulent murine coronavirus. May 11-12, 2007. 2nd Annual Neuroinflammation Symposium. Château Bromont, Bromont, Canada. | ||
*'''Gabriel Marceau''' and Pierre Talbot. Immunomodulation by a neurovirulent murine coronavirus. 9-12 | *'''Gabriel Marceau''' and Pierre Talbot. Immunomodulation by a neurovirulent murine coronavirus. June 9-12, 2006. Canadian Society for Immunology 2006 Annual Meeting. The Westin Nova Scotian Hotel, Halifax, Canada. | ||
*'''Gabriel Marceau''' et Pierre J. Talbot. [ | *'''Gabriel Marceau''' et Pierre J. Talbot. [Caracterisation of autoimmunity induced by the murine coronavirus in a model of demyelination of the central nervous system]-French. November 3-5, 2005. 4ème Congrès Armand-Frappier. Auberge du Lac-à-l’Eau-Claire, Canada. | ||
*Pascal Lapierre, '''Gabriel Marceau''', Hugo Soudeyns and Fernando Alvarez. Autoantibodies in Hepatitis C Chronic Infection: A Case of Molecular Mimicry? 18-23 | *Pascal Lapierre, '''Gabriel Marceau''', Hugo Soudeyns and Fernando Alvarez. Autoantibodies in Hepatitis C Chronic Infection: A Case of Molecular Mimicry? July 18-23, 2004. 12th International Congress of Immunology. Palais des Congrès, Montréal, Canada. Clin. Invest. Med., 27: 91A (M6.83), 2004. | ||
*'''Gabriel Marceau''', Pascal Lapierre, Hugo Soudeyns and Fernando Alvarez. (Poster of distinction) Hepatitis C virus chronic infection with anti-cytochrome P450IID6 autoantibodies : implication of molecular mimicry. 2-5 | *'''Gabriel Marceau''', Pascal Lapierre, Hugo Soudeyns and Fernando Alvarez. (Poster of distinction) Hepatitis C virus chronic infection with anti-cytochrome P450IID6 autoantibodies : implication of molecular mimicry. October 2-5, 2003. North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) 16th Annual meeting. Hotel Fairmont Queen Elisabeth, Montréal, Canada. JPGN, 37: 380 (A160), 2003. | ||
*'''Gabriel Marceau''', Pascal Lapierre, Hugo Soudeyns et Fernando Alvarez. [Infection par le virus de l’hépatite C et autoanticorps dirigés contre le cytochrome P450IID6 : rôle du mimétisme moléculaire]-French. 22 | *'''Gabriel Marceau''', Pascal Lapierre, Hugo Soudeyns et Fernando Alvarez. [Infection par le virus de l’hépatite C et autoanticorps dirigés contre le cytochrome P450IID6 : rôle du mimétisme moléculaire]-French. January 22, 2003. Congrès des stagiaires de recherche en santé de la Faculté de médecine, du CHUM et des Centres hospitaliers et instituts affiliés à l’Université de Montréal. Palais des Congrès, Montréal, Canada. Médecine Sciences, 19: S40 (A220), 2003. | ||
</blockquote> | </blockquote> | ||
Revision as of 19:14, 13 February 2011
Contact Information
Regular mail (aka slow mail)
CHU Sainte-Justine
Laboratory of pediatric liver diseases, Dr Fernando Alvarez
3175 chemin de la Côte-Ste-Catherine
Montreal, Québec
Canada, H3T 1C5
(514) 345-4834
e-mail
gabriel_marceau AT yahoo DOT ca
Research Interests
General Interests
- Virology
- Antigenic mimicry
- Immune Evasion
- Neurovirology
- Immunology
- Neuroimmunology
- History (particularly science)
Techniques
- Histology
- Cryostat ultra thin sections
- Hematoxylin and eosin staining
- Luxol fast blue staining
- Immunohistochemistry labelling antibodies / DAB
- Molecular biology
- Molecular cloning
- Protein production in bacteria
- Protein purification (antibodies)
- Immunology
- Flow cytometry
- ELISA
- Proliferation assays
- Virology
- Amplification
- Plaque forming assay titration
- Detection by polymerase chain reaction (PCR)
- Cell culture (primary and cell lines)
- Mouse spleen cells
- Liver infiltrating lymph nodes
- Purification and culture of mouse T lymphocytes
- Spleen
- Lymph nodes
- Liver
- Central nervous system
- Animal experimentation
- Mouse
Protocols
Education
Diplomas
- Ph.D. Virology and immunology, INRS - Institut Armand-Frappier, Laval, Canada, 2003-2010
- M.Sc. Microbiology and immunology, Université de Montréal, Montréal, Canada, 2001-2003
- B.Sc. Molecular biology and biotechnology, Université du Québec à Montréal, Montréal, Canada, 1997-2001
Scholarships
- Travel Award, NeuroInflammation Training Program (IRSC/FRSQ), 2008
- Travel Award, Fondation Armand-Frappier, 2007
- Travel Award, NeuroInflammation Training Program (IRSC/FRSQ), 2007
- Award, Multiple Sclerosis Society of Canada, 2007-2008
- Travel Award, NeuroInflammation Training Program (IRSC/FRSQ), 2006
- Award, Fondation Armand-Frappier / RBC Groupe Financier, 2005-2006
- Award, NeuroInflammation Training Program (IRSC/FRSQ), 2004-2006
- Award, Fondation Armand-Frappier / RBC Groupe Financier, 2004-2005
- Award, Fondation Armand-Frappier / RBC Groupe Financier, 2003-2004
- Award, Département microbiologie et immunologie, Université de Montréal, 2002
Publications
Papers
- Jacomy H, St-Jean JR, Brison E, Marceau G, Desforges M, and Talbot PJ. Mutations in the spike glycoprotein of human coronavirus OC43 modulate disease in BALB/c mice from encephalitis to flaccid paralysis and demyelination. J Neurovirol. 2010 Jul;16(4):279-93. DOI:10.3109/13550284.2010.497806 |
- Marceau G, Lapierre P, Béland K, Soudeyns H, and Alvarez F. LKM1 autoantibodies in chronic hepatitis C infection: a case of molecular mimicry?. Hepatology. 2005 Sep;42(3):675-82. DOI:10.1002/hep.20816 |
- Vitozzi S, Lapierre P, Djilali-Saiah I, Marceau G, Beland K, and Alvarez F. Anti-soluble liver antigen (SLA) antibodies in chronic HCV infection. Autoimmunity. 2004 May;37(3):217-22. DOI:10.1080/08916930410001686260 |
- Béland K, Lapierre P, Marceau G, and Alvarez F. Anti-LC1 autoantibodies in patients with chronic hepatitis C virus infection. J Autoimmun. 2004 Mar;22(2):159-66. DOI:10.1016/j.jaut.2003.11.001 |
Books/Sections
Francine Lambert, Hélène Jacomy, Gabriel Marceau, Pierre J. Talbot. Chapter 8: Titration of human coronaviruses, HCoV-229E and HCoV-OC43, by an Indirect Immunoperoxidase Assay.
Master's thesis
- Gabriel Marceau. 2003. [Infection by hepatitis C virus and autoantibodies against cytochrome P450IID6: role of molecular mimicry]-French. Université de Montréal.
Doctoral thesis
- Gabriel Marceau. 2010. [Transient immunosuppression in a mouse model of multiple sclerosis]-French. INRS - Institut Armand-Frappier.
Meeting communications
Talks
- Igal Ifergan, Hania Kebir, Gabriel Marceau, Monique Bernard, Pierre Talbot, Nathalie Arbour and Alexandre Prat. VLA-4-Dependent Recruitment of Effector Memory CD8+ T Lymphocytes into the Central Nervous System. FOCIS2009 June 11-14, 2009. San Francisco, CA, USA. Clin Immunol, 131: S11 (S1), 2009.
- Gabriel Marceau and Pierre Talbot. Immunomodulation by a neurovirulent coronavirus. 57th Annual Meeting of the Canadian Society for Microbiologists June 17-20, 2007. Université Laval, Québec, Canada.
- Gabriel Marceau et Pierre Talbot. [Immunomodulation by a neurovirulent coronavirus]-French. May 18, 2006. Colloque – Dialogues entre le système nerveux central et le système immunitaire. 74ème Congrès de l’ACFAS: Le savoir trame de la modernité du 15 au 19 mai 2006. Université McGill, Montréal, Canada.
- Gabriel Marceau and Pierre Talbot. Immunomodulation by a neurovirulent murine coronavirus. Mai 12, 2006. 1st Annual Neuroinflammation Symposium. Douglas Hospital, Montréal, Canada.
- Gabriel Marceau, Pascal Lapierre, Hugo Soudeyns et Fernando Alvarez. [Infection by hepatitis C virus and autoantibodies against cytochrome P450IID6: role of molecular mimicry]-French. November 6-8, 2003. Congrès INRS-Institut Armand-Frappier 2003. Manoir du Lac Delage, Stoneham, Canada.
- Kathie Béland, Pascal Lapierre, Gabriel Marceau and Fernando Alvarez. Anti-LC1 autoantibodies in patients with chronic hepatitis C virus infection. October 2-5, 2003. North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) 16th Annual meeting. Hotel Fairmont Queen Elisabeth, Montréal, Canada. JPGN, 37: 393 (A211), 2003.
- Gabriel Marceau, Pascal Lapierre, Hugo Soudeyns et Fernando Alvarez. [Infection by hepatitis C virus and autoantibodies against cytochrome P450IID6: role of molecular mimicry]-French. June 6, 2003. XVIIIème congrès annuel de la recherche des étudiants gradués et post-gradués. Centre de recherche de l’Hôpital Ste-Justine, Montréal, Canada.
Posters
- Gabriel Marceau, Hélène Jacomy, Marc Desforges, Claude Daniel and Pierre J. Talbot. Transient immunosuppression by a neurovirulent coronavirus in an animal model of multiple sclerosis. June 22-27, 2008. XIth International Nidovirus Symposium. St. Catherine’s College Oxford, UK.
- Gabriel Marceau and Pierre J. Talbot. Immunomodulation by a neurovirulent murine coronavirus. December 7-10 2007. EndMS.ca. Fairmont Banffsprings, Banff, Canada.
- Gabriel Marceau and Pierre Talbot. Immunomodulation by a neurovirulent murine coronavirus. May 11-12, 2007. 2nd Annual Neuroinflammation Symposium. Château Bromont, Bromont, Canada.
- Gabriel Marceau and Pierre Talbot. Immunomodulation by a neurovirulent murine coronavirus. June 9-12, 2006. Canadian Society for Immunology 2006 Annual Meeting. The Westin Nova Scotian Hotel, Halifax, Canada.
- Gabriel Marceau et Pierre J. Talbot. [Caracterisation of autoimmunity induced by the murine coronavirus in a model of demyelination of the central nervous system]-French. November 3-5, 2005. 4ème Congrès Armand-Frappier. Auberge du Lac-à-l’Eau-Claire, Canada.
- Pascal Lapierre, Gabriel Marceau, Hugo Soudeyns and Fernando Alvarez. Autoantibodies in Hepatitis C Chronic Infection: A Case of Molecular Mimicry? July 18-23, 2004. 12th International Congress of Immunology. Palais des Congrès, Montréal, Canada. Clin. Invest. Med., 27: 91A (M6.83), 2004.
- Gabriel Marceau, Pascal Lapierre, Hugo Soudeyns and Fernando Alvarez. (Poster of distinction) Hepatitis C virus chronic infection with anti-cytochrome P450IID6 autoantibodies : implication of molecular mimicry. October 2-5, 2003. North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) 16th Annual meeting. Hotel Fairmont Queen Elisabeth, Montréal, Canada. JPGN, 37: 380 (A160), 2003.
- Gabriel Marceau, Pascal Lapierre, Hugo Soudeyns et Fernando Alvarez. [Infection par le virus de l’hépatite C et autoanticorps dirigés contre le cytochrome P450IID6 : rôle du mimétisme moléculaire]-French. January 22, 2003. Congrès des stagiaires de recherche en santé de la Faculté de médecine, du CHUM et des Centres hospitaliers et instituts affiliés à l’Université de Montréal. Palais des Congrès, Montréal, Canada. Médecine Sciences, 19: S40 (A220), 2003.
Other Interests
Student Affairs
Present
- None
Past (AGEIAF INRS - Institut Armand-Frappier)
- Student Representative, Documentation Services Committee
- Student Representative, Virology and Immunology Program Committee
- Student Representative, Biosecurity Committee
Scientific Associations
Other Associations
My pages
- To Do
- My Sandbox
- My Softwares
- My Library
- Wiki help pages