User:Gabriel Marceau

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Contents

Contact Information

Snail mail

ITR Laboratories
Baie d'Urfé, Québec
Canada


e-mail
marceau DOT gabriel AT gmail DOT com

links
Academia.edu
BiomedExperts
LabRoots
LinkedIn
ORCID
Research Gate

Research Interests

General Interests

  • Virology
    • Antigenic mimicry
    • Immune Evasion
    • Neurovirology
  • Immunology
    • Neuroimmunology
  • History (particularly science)

Techniques

  • Histology
    • Cryostat ultra thin sections
    • Hematoxylin and eosin staining
    • Luxol fast blue staining
    • Immunohistochemistry labelling antibodies / DAB
  • Molecular biology
    • Molecular cloning
    • Protein production in bacteria
    • Protein purification (antibodies)
  • Immunology
    • Flow cytometry
    • ELISA
    • Proliferation assays
  • Virology
    • Amplification
    • Plaque forming assay titration
    • Detection by polymerase chain reaction (PCR)
  • Cell culture (primary and cell lines)
    • Mouse spleen cells
    • Liver infiltrating lymph nodes
    • Purification and culture of mouse T lymphocytes
      • Spleen
      • Lymph nodes
      • Liver
      • Central nervous system
  • Animal experimentation
    • Mouse

Protocols

Education

Diplomas

Scholarships

Publications

Papers

  1. Marceau G, Yang R, Lapierre P, Béland K, and Alvarez F. . pmid:24517723. PubMed HubMed [Marceau2014]
    (2014). Low-dose anti-CD3 antibody induces remission of active autoimmune hepatitis in xenoimmunized mice. Liver International. DOI:10.1111/liv.12498.

  2. Ifergan I, Kebir H, Alvarez JI, Marceau G, Bernard M, Bourbonnière L, Poirier J, Duquette P, Talbot PJ, Arbour N, and Prat A. . pmid:22058139. PubMed HubMed [Ifergan2011]
    (2011). Central nervous system recruitment of effector memory CD8+ T lymphocytes during neuroinflammation is dependent on α4 integrin. Brain, 134: 3557-74.

  3. Jacomy H, St-Jean JR, Brison E, Marceau G, Desforges M, and Talbot PJ. . pmid:20642316. PubMed HubMed [Jacomy2010]
    (2010). Mutations in the spike glycoprotein of human coronavirus OC43 modulate disease in BALB/c mice from encephalitis to flaccid paralysis and demyelination. Journal of Neurovirology, 16: 280-294.

  4. Marceau G, Lapierre P, Béland K, Soudeyns H, and Alvarez F. . pmid:16037945. PubMed HubMed [Marceau2005]
    (2005). LKM1 autoantibodies in chronic hepatitis C infection: a case of molecular mimicry? Hepatology, 42: 675-682.

  5. Vitozzi S, Lapierre P, Djilali-Saiah I, Marceau G, Beland K, and Alvarez F. . pmid:15497455. PubMed HubMed [Vitozzi2004]
    (2004). Anti-Soluble Liver Antigen (SLA) Antibodies in Chronic HCV Infection. Autoimmunity, 37: 217-222.

  6. Béland K, Lapierre P, Marceau G, and Alvarez F. . pmid:14987745. PubMed HubMed [Beland2004]
    (2004). Anti-LC1 autoantibodies in patients with chronic hepatitis C virus infection. Journal of Autoimmunity, 22: 159-166.

All Medline abstracts: PubMed HubMed

Books/Sections

  1. Dave Cavanagh (Editor). SARS- and Other Coronaviruses: Laboratory Protocols. Humana Press. isbn:9781588298676. [Lambert2008]
Francine Lambert, Hélène Jacomy, Gabriel Marceau, Pierre J. Talbot. Chapter 8: Titration of human coronaviruses, HCoV-229E and HCoV-OC43, by an Indirect Immunoperoxidase Assay.

Master's thesis

  • Gabriel Marceau. 2003. [Infection by hepatitis C virus and autoantibodies against cytochrome P450IID6: role of molecular mimicry]-French. Université de Montréal.

Doctoral thesis

Meeting communications

Invited Lecturer

  • Transient Immunosuppression Induced by a Neurovirulent Coronavirus in an Animal Model of Multiple Sclerosis. Internationales Graduiertenkolleg 1522. Institut für Virologie und Immunobiologie, Universität Würzburg. 19 avril 2011. Würzburg, Free State of Bavaria, Germany.

Talks

  • Kathie Béland, Roland Yang, Boury Faye, Marie-France Gagnon, Gabriel Marceau, Pascal Lapierre, and Fernando Alvarez. Intranasal desensitisation as a new targeted treatment for type 2 autoimmune hepatitis in a murine model through the generation of regulatory cells populations. 9 au 13 novembre 2012. 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD). Boston, MA, USA. Hepatology, 56: 86A (221), 2012.
  • Gabriel Marceau, Pascal Lapierre, Kathie Béland, Roland Yang, and Fernando Alvarez, B Lymphocytes depletion therapy for autoimmune hepatitis. 24-27 february 2012. Canadian Digestive Diseases Week and Annual CASL Winter Meeting. Fairmont Queen Elizabeth, Montreal, Quebec, Canada.
  • Kathie Béland, Roland Yang, Boury Faye, Marie-France Gagnon, Gabriel Marceau, Pascal Lapierre, Fernando Alvarez, Intranasal desensitisation as a new targeted treatment for type 2 autoimmune hepatitis in a murine model. 24-27 february 2012. Canadian Digestive Diseases Week and Annual CASL Winter Meeting. Fairmont Queen Elizabeth, Montreal, Quebec, Canada.
  • Catherine Habel, Kathie Béland, Gabriel Marceau, Chantal Piché, C Marquet et Fernando Alvarez. [Induction of Immunological Tolerance by DNA Vaccination in a Mouse Model of Autoimmune Hepatitis]-french. June 8, 2011. XXVIe annual research meeting of graduate and postgraduate students. Research Center, Ste-Justine Hospital, Montreal, Canada.
  • Igal Ifergan, Hania Kebir, Gabriel Marceau, Monique Bernard, Pierre Talbot, Nathalie Arbour and Alexandre Prat. VLA-4-Dependent Recruitment of Effector Memory CD8+ T Lymphocytes into the Central Nervous System. FOCIS2009 June 11-14, 2009. San Francisco, CA, USA. Clin Immunol, 131: S11 (S1), 2009.
  • Gabriel Marceau and Pierre Talbot. Immunomodulation by a neurovirulent coronavirus. 57th Annual Meeting of the Canadian Society for Microbiologists June 17-20, 2007. Université Laval, Québec, Canada.
  • Gabriel Marceau et Pierre Talbot. [Immunomodulation by a neurovirulent coronavirus]-French. May 18, 2006. Colloque – Dialogues entre le système nerveux central et le système immunitaire. 74ème Congrès de l’ACFAS: Le savoir trame de la modernité du 15 au 19 mai 2006. Université McGill, Montréal, Canada.
  • Gabriel Marceau and Pierre Talbot. Immunomodulation by a neurovirulent murine coronavirus. Mai 12, 2006. 1st Annual Neuroinflammation Symposium. Douglas Hospital, Montréal, Canada.
  • Gabriel Marceau, Pascal Lapierre, Hugo Soudeyns et Fernando Alvarez. [Infection by hepatitis C virus and autoantibodies against cytochrome P450IID6: role of molecular mimicry]-French. November 6-8, 2003. Congrès INRS-Institut Armand-Frappier 2003. Manoir du Lac Delage, Stoneham, Canada.
  • Kathie Béland, Pascal Lapierre, Gabriel Marceau and Fernando Alvarez. Anti-LC1 autoantibodies in patients with chronic hepatitis C virus infection. October 2-5, 2003. North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) 16th Annual meeting. Hotel Fairmont Queen Elisabeth, Montréal, Canada. JPGN, 37: 393 (A211), 2003.
  • Gabriel Marceau, Pascal Lapierre, Hugo Soudeyns et Fernando Alvarez. [Infection by hepatitis C virus and autoantibodies against cytochrome P450IID6: role of molecular mimicry]-French. June 6, 2003. XVIIIème congrès annuel de la recherche des étudiants gradués et post-gradués. Centre de recherche de l’Hôpital Ste-Justine, Montréal, Canada.

Posters

  • Gabriel Marceau, Lev Kolodziesky, Guillaume Diagne, Julie Temblay, Sybil Thébaud, Miglena Toneva, Kelly Scribner Doering, C Kostrub, and Andrew Nelson. Acute Injury Biomarkerts Following Low Dose Gentamicin Treatment of Rats. March 24-27, 2014. Society of Toxicology's 53rd Annual Meeting. Phoenix, Arizona, USA. The Toxicologist (Toxicological Sciences), 138: 72 (286), 2014.
  • * Gabriel Marceau, Kathie Béland, Pascal Lapierre, et Fernando Alvarez. (Poter of distinction) B Lymphocytes Depletion Therapy in a Mouse Model of Autoimmune Hepatitis . November 9-13, 2012. 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD). Boston, MA, USA. Hepatology, 56: 186A (1975), 2012.
  • Sara Bourbonnais, Gabriel Marceau, Kathie Béland, et Fernando Alvarez . Study of the pregnancy-induced remission of autoimmune hepatitis, in a murine model . November 9-13, 2012. 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD). Boston, MA, USA. Hepatology, 56: 171A (1719), 2012.
  • * Sara Bourbonnais, Gabriel Marceau, Kathie Béland et Fernando Alvarez. (Poster of distinction). Impact of pregnancy in a murine model of autoimmune hepatitis. 24-27 february 2012. Canadian Digestive Diseases Week and Annual CASL Winter Meeting. Fairmont Queen Elizabeth, Montreal, Quebec, Canada.
  • Gabriel Marceau, Hélène Jacomy, Marc Desforges, Claude Daniel and Pierre J. Talbot. Transient immunosuppression by a neurovirulent coronavirus in an animal model of multiple sclerosis. June 22-27, 2008. XIth International Nidovirus Symposium. St. Catherine’s College Oxford, UK.
  • Gabriel Marceau and Pierre J. Talbot. Immunomodulation by a neurovirulent murine coronavirus. December 7-10 2007. EndMS.ca. Fairmont Banffsprings, Banff, Canada.
  • Gabriel Marceau and Pierre Talbot. Immunomodulation by a neurovirulent murine coronavirus. May 11-12, 2007. 2nd Annual Neuroinflammation Symposium. Château Bromont, Bromont, Canada.
  • Gabriel Marceau and Pierre Talbot. Immunomodulation by a neurovirulent murine coronavirus. June 9-12, 2006. Canadian Society for Immunology 2006 Annual Meeting. The Westin Nova Scotian Hotel, Halifax, Canada.
  • Gabriel Marceau et Pierre J. Talbot. [Caracterisation of autoimmunity induced by the murine coronavirus in a model of demyelination of the central nervous system]-French. November 3-5, 2005. 4ème Congrès Armand-Frappier. Auberge du Lac-à-l’Eau-Claire, Canada.
  • Pascal Lapierre, Gabriel Marceau, Hugo Soudeyns and Fernando Alvarez. Autoantibodies in Hepatitis C Chronic Infection: A Case of Molecular Mimicry? July 18-23, 2004. 12th International Congress of Immunology. Palais des Congrès, Montréal, Canada. Clin. Invest. Med., 27: 91A (M6.83), 2004.
  • * Gabriel Marceau, Pascal Lapierre, Hugo Soudeyns and Fernando Alvarez. (Poster of distinction) Hepatitis C virus chronic infection with anti-cytochrome P450IID6 autoantibodies : implication of molecular mimicry. October 2-5, 2003. North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) 16th Annual meeting. Hotel Fairmont Queen Elisabeth, Montréal, Canada. JPGN, 37: 380 (A160), 2003.
  • Gabriel Marceau, Pascal Lapierre, Hugo Soudeyns et Fernando Alvarez. [Infection par le virus de l’hépatite C et autoanticorps dirigés contre le cytochrome P450IID6 : rôle du mimétisme moléculaire]-French. January 22, 2003. Congrès des stagiaires de recherche en santé de la Faculté de médecine, du CHUM et des Centres hospitaliers et instituts affiliés à l’Université de Montréal. Palais des Congrès, Montréal, Canada. Médecine Sciences, 19: S40 (A220), 2003.

* Poster of distinction

Other Interests

Student Affairs

Past (AGEIAF INRS - Institut Armand-Frappier)
  • Student Representative, Documentation Services Committee
  • Student Representative, Virology and Immunology Program Committee
  • Student Representative, Biosecurity Committee

Scientific Associations


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