User:Liuzhec
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Project Overview
- Our goal is to design and implement molecular containers, which can be dynamically opened and closed by an external stimulus.
- The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility.
- As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers.
- We expect that molecular containers could have several interesting scientific and clinical applications, such as
- Drug and gene delivery
- Bio-marker scavenging (early detection of biomarkers)
- Directed evolution (compartmentalized selections)
- Using multiplexing for combinatorial chemical synthesis
- Capture and stabilization of multiprotein complexes
- Protein folding (chaperones)
- Cell sorting
==Working Team Members== edit
- Tiffany Chan (talk, edits)
- Katherine Fifer (talk, edits)
- Valerie Lau (talk, edits)
- Matthew Meisel (talk, edits)
- Lewis Hahn (talk, edits)
- TA: Shawn Douglas (talk, edits)
Recent Changes
List of abbreviations:
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25 April 2024
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00:22 | The paper that launched microfluidics - Xi Ning 7 changes history +4,723 [Xning098 (7×)] | |||
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24 April 2024
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18:35 | User:Yanbin Huang 2 changes history +25 [Yanbin Huang (2×)] | |||
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08:14 | "Pick and Place" Assembly of Parts Using PDMS - Amy Lim, Rylie Costello 6 changes history +394 [Rcostello (6×)] | |||
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