BME100 f2013:Projects1

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BME 100 Fall 2013 Home
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Lab Write-Up 1 | Lab Write-Up 2 | Lab Write-Up 3
Lab Write-Up 4 | Lab Write-Up 5 | Lab Write-Up 6
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Lab 1: “Designing an Experiment”

• Review of the scientific method
• Design of an effective experiment
• Implementation of statistics in Excel

Topics/Terms:
- Independent and Dependent Variables
- Experimental and Control groups
- Randomization
- Sample size
- Bias
- T-test and ANOVA

Mini-problem: This semester, you and your team are assisting a graduate student, Kristen, in a research lab. You are studying the effects of inflammation, but the lab is short on cash. You must determine the lowest possible dose of an inflammation inducing agent (lipopolysaccharide) to increase a newly discovered inflammatory protein (Inflammotin) in the elderly. The protein is measured in blood samples using ELISA. Prior work as shown that 10mg pill of lipopolysaccharide can increase protein levels so this is a good starting point.

Assignment:
1. What are your independent and dependent variables?
2. Describe your experimental design.
a. How many groups?
b. How many subjects/group?
3. How will you select your subjects?
4. What are some of the potential sources of error or biases that could affect your results and how would you control for them?

HW: Lab Report 1 (due 9/11/13 through OpenWetWare)

Grading Scheme:
10 points – Identification of independent and dependent variables
30 points – Experimental Design
20 points – Subject Selection
20 points – Sources of Error and Controls
20 points – Individual Contribution (as noted by OpenWetWare editing records)



Wednesday, 9:00 AM

Group 1 Group 2 Group 3 Group 4 Group 5
Group 6 Group 7 Group 8 Group 9 Group 10
Group 11 Group 12 Group 13 Group 14 Group 15
Group 16 Group 17 Group 18 Group 19 Group 20



Wednesday, 12:00 PM

Group 1 Group 2 Group 3 Group 4 Group 5
Group 6 Group 7 Group 8 Group 9 Group 10
Group 11 Group 12 Group 13 Group 14 Group 15
Group 16 Group 17 Group 18 Group 19 Group 20
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