BME100 f2015:Group11 8amL1

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Contents

OUR TEAM

Name: Dean Spyres
Name: Dean Spyres
Name: Kyle Greenzweig
Name: Kyle Greenzweig
Name: Maria Roman
Name: Maria Roman
Name: Kyra Temple
Name: Kyra Temple
Name: Ryan Tenorio
Name: Ryan Tenorio
Name: Theodore Valenzuela
Name: Theodore Valenzuela

LAB 1 WRITE-UP

Independent and Dependent Variables

Independent variable-the amount of lipopolysaccharide given to the elderly, because we have control over the dosage levels and we vary it from 0mg to 10mg, it’s the only variable that we are changing

Dependent variable- the amount of Inflammotin, a protein that presents itself in a blood sample. The levels are being impacted by the independent variable, this is the amount being measured.

Experimental Design

Groups

6 groups increasing by 2 mg from 0mg to 10 mg, we needed to keep costs down and represent a broad spectrum to get an idea of the optimal dosage.


Age

65-80 years old

Number of subjects per group


15 subjects per group, since we have an age range of 15 years we needed 15 people per group to reduce the variability between ages




Subject Selection

65-85 years, a mixture of genders and health levels. We present a control of 10mg and 0mg to compare the results between each group.





Sources of Error and Bias

Outliers; people above (or below) a certain age might not react to the drug the same way, health levels of the subject would vary and their reaction to the drug could be effected if they have preexisting health conditions. Accuracy of lowest dosage; the gap between dosages given too each group may inhibit our ability to pinpoint the optimal (lowest) dosage accurately. Time between dosage and the reading needs to be consistent between all subjects. Our biases are present toward the lower end of our dosage spectrum.







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