BME100 f2015:Group16 1030amL2
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Lab Number 2: Using Statistics to measure and analyze data
Results for effect of drug on RATS:
| ' | ' | ' | ' |
| Dosage | Average | Standard Deviation | Standard Error |
| 0mg | 9.24 | 2.225551617 | 0.995296941 |
| 10mg | 11.112 | 7.402885924 | 3.310671 |
| Dosage | Average | Standard Deviation | Standard Error |
| 0 mg | 3.834 | 1.444854 | 0.456903 |
| 5 mg | 8.932 | 1.512136 | 0.478179 |
| 10 mg | 61.622 | 28.56551 | 9.033208 |
| 15 mg | 657.941 | 202.0154 | 63.88289 |
Effect of Inflammotin on HUMAN Subjects.
Effect of Inflammotin on RAT Subjects.
Single Factor ANOVA Test for HUMAN Subjects
| SUMMARY | ' | ' | ' | ' |
| Groups | Count | Sum | Average | Variance |
| 0 mg | 10 | 38.34 | 3.834 | 2.31956 |
| 5 mg | 10 | 89.32 | 8.932 | 2.540617778 |
| 10 mg | 10 | 616.22 | 61.622 | 906.6538844 |
| 15 mg | 10 | 6579.41 | 657.941 | 45344.71112 |
| ANOVA | ' | ' | ' | ' | ' | ' |
| Source of Variation | SS | df | MS | F | P-value | F crit |
| Between Groups | 3027016.695 | 3 | 1009005.565 | 87.25360195 | 1.40E-16 | 2.866265551 |
| Within Groups | 416306.0267 | 36 | 11564.0563 | |||
| Total | 3443322.721 | 39 | ||||
Post HOC T-Test for Human Subjects
Summary: The study and experiments show that as as the amount of LPS was increased in both study subjects, the inflammation levels also increased. In regards to the Rat experimental group, as the dosage was increased from 0 mg to 10 mg, the average inflammation levels in all of the subjects also increased (from an average of 9.24 pg/ml to 11.112 pg/ml). For the human test subject counterparts, similar results concurred with the data received from the rats. As the dosage was slowly increased in humans, from 0 mg to 5 mg to 10 mg and finally to 15 mg, the inflammation levels increased exponentially. Also, our one factor ANOVA test and unpaired t test came up with a value greater than 95%, which means that the data is statistically significant in both studies. Overall, a positive correlation and possible causation of LPS being positively correlated with Inflammation levels in both humans and rats is noticed.| Post-hoc Tests | t-test value | Corrected p-value to achieve significance | Significant? |
| 0mg vs. 5mg | 8.59631E-07 | 0.0167 | Yes |
| 0mg vs. 10mg | 9.94377E-06 | 0.0167 | Yes |
| 0mg vs. 15mg | 1.39436E-08 | 0.0167 | Yes |
| 5mg vs. 10mg | 3.01859E-05 | 0.0167 | Yes |
| 5mg vs.15mg | 1.57101E-08 | 0.0167 | Yes |
| 10mg vs. 15mg | 6.4824E-08 | 0.0167 | Yes |
