Kristoffer Chin: Week 5

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Contents

Question

The question we are asking for week 5 is if there are specific differences nucleotide sequences that cause an increase in the rate of CD4 T cells decline in rapid progressors compared to non-progressors.

Hypothesis

We believe that there will be a difference in the nucleotide sequences found in the nucleotide sequences in rapid progressors and non-progressors

Subjects

  • For the group of rapid progressors, we have chosen 4-V2, 4-V3, 4-V4, 10-V4, 10-V5, 10-V6, 11-V2, 11-V3, 11-V4. These subjects were chosen because they had the highest frequencies of visit which allowed a better variable of CD4 T cells to choose from. These specific visits were chosen because they had the highest rate of CD4 T Cell decline
  • For the group of non-progressors, we have chosen 2-V1, 2-V3, 2-V4, 12-V3, 12-V4, 12-V5, 13-V2, 13-V3, 13-V5. These subjects were chosen because they were the only recorded nonprogressors in the experiment. These visits were chosen because they had the highest CD4 T cell count among all visits.
  • All clones will also be analyzed for each visit to find a difference in the nucleotide sequence.

Journal articles

  1. Borrego P, Marcelino JM, Rocha C, Doroana M, Antunes F, Maltez F, Gomes P, Novo C, Barroso H, and Taveira N. . pmid:18778482. PubMed HubMed [Paper1]
  2. Hill MD and Hernández W. . pmid:16385396. PubMed HubMed [Paper2]
  3. Templeton AR, Reichert RA, Weisstein AE, Yu XF, and Markham RB. . pmid:15342497. PubMed HubMed [Paper3]
  4. Deckers R, Quesson B, Arsaut J, Eimer S, Couillaud F, and Moonen CT. . pmid:19164593. PubMed HubMed [Paper4]
  5. Deckers R, Quesson B, Arsaut J, Eimer S, Couillaud F, and Moonen CT. . pmid:19164593. PubMed HubMed [Paper5]
All Medline abstracts: PubMed HubMed

BIOL398-01: Bioinformatics Lab

  • Lab Journal
Kristoffer Chin: Week 2 Kristoffer Chin: Week 6 Kristoffer Chin: Week 11
Kristoffer Chin: Week 3 Kristoffer Chin: Week 7 Kristoffer Chin: Week 12
Kristoffer Chin: Week 4 Kristoffer Chin: Week 8 Kristoffer Chin: Week 13
Kristoffer Chin: Week 5 Kristoffer Chin: Week 9 Kristoffer Chin: Week 14


  • Shared Journal
BIOL398-01/S10:Class Journal Week 2 BIOL398-01/S10:Class Journal Week 6 BIOL398-01/S10:Class Journal Week 11
BIOL398-01/S10:Class Journal Week 3 BIOL398-01/S10:Class Journal Week 7 BIOL398-01/S10:Class Journal Week 12
BIOL398-01/S10:Class Journal Week 4 BIOL398-01/S10:Class Journal Week 8 BIOL398-01/S10:Class Journal Week 13
BIOL398-01/S10:Class Journal Week 5 BIOL398-01/S10:Class Journal Week 9 BIOL398-01/S10:Class Journal Week 14


  • Assignments
BIOL398-01/S10:Week 2 BIOL398-01/S10:Week 6 BIOL398-01/S10:Week 11
BIOL398-01/S10:Week 3 BIOL398-01/S10:Week 7 BIOL398-01/S10:Week 12
BIOL398-01/S10:Week 4 BIOL398-01/S10:Week 8 BIOL398-01/S10:Week 13
BIOL398-01/S10:Week 5 BIOL398-01/S10:Week 9 BIOL398-01/S10:Week 14

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