User:James Chappell

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James Chappell

Research Interests

I am currently working as a postdoctoral researcher with Prof. Julius Lucks (Lucks Lab) at Cornell University in the School of Chemical and Biomolecular Engineering. I previously obtained a BSc degree in Biochemistry at Imperial College London, where I continued as a PhD student in Molecular Biosciences under the supervision of Prof. Paul Freemont working at the Imperial College Center for Synthetic Biology and Innovation. My research interests are broadly focused in Synthetic Biology.


1. M. K. Takashashi, J. Chappell, C. A. Hayes, Z. Z. Sun, J. Kim, V. Singhal, K. J. Spring, S. Al-Khabouri, C. P. Fall, V. Noireaux, R. M. Murray, J. B. Lucks. Rapidly characterizing the fast dynamics of RNA genetic circuitry with cell-free transcription-translation (TX-TL) systems. ACS Synthetic Biology, 2014. DOI: 10.1021/sb400206c

2. J. Chappell, M. K. Takashashi, S. Meyer, D. Loughrey, K. Watters, J. B. Lucks. The Centrality of RNA for Engineering Gene Expression. Biotechnology Journal, 2013. DOI: 10.1002/biot.201300018

3. J. Chappell, K. Jensen, and P. S. Freemont. Validation of an entirely in vitro approach for rapid prototyping of DNA regulatory elements for synthetic biology. Nucleic Acids Res, 2013. DOI: 10.1093/nar/gkt052

4. J. Chappell, P. S. Freemont. Synthetic Biology—A New Generation Of Biofilm Biosensors. The Science and Applications of, Synthetic and Systems Biology, 8. 2011. Pubmed Link

5. J. Chappell, P. S. Freemont. In Vivo and In Vitro Characterization of σ 70 Constitutive Promoters by Real-Time PCR and Fluorescent Measurements. Synthetic Biology (Methods in Molecular Biology), 2013. Pubmed Link

6. S. Gulati, V. Rouilly, X. Niu, J. Chappell, R. I. Kitney, J. B. Edel, P. S. Freemont and P. A, deMello. Opportunities for microfluidic technologies in synthetic biology. Journal of The Royal Society Interface, 2009. DOI: 10.1098/​rsif.2009.0083.focu

Contact Details

James Chappell,
120 Olin Hall,
Chemical and Biomolecular Engineering

Email -

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