User:Jarle Pahr/Metabolic engineering

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Notes on metabolic engineering:



Copeland 2012. Computational tools for metabolic engineering:

Keasling 2012. Synthetic biology and the development of tools for metabolic engineering:

D. Chandran, F.T. Bergmann, H.M. Sauro. Computer-aided design of biological circuits using TinkerCell.



Model SEED:


Persons and researchg groups

Gregory Stephanopoulos

Jay D Keasling.


Metabolic Engineering:


Microbial Cell factories

Journal of Biological Engineering



Modification of glucose import capacity in Escherichia coli: physiologic consequences and utility for improving DNA vaccine production:,_Ecotoxicology_and_Bioremediation/10.3389/fmicb.2013.00200/abstract

Demain, A.L. and S. Sanches. 2007. Microbial synthesis of primary metabolites: Current advances and future prospects. In Fermentation microbiology and biotechnology (eds. Mansi, Bryce, Demain and Allman).

Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels:

Metabolic engineeringof Escherichia coli for theproductionofsuccinate from glycerol:

Microbial production of fatty-acid-derived fuels and chemicals from plant biomass:

ePathBrick: A Synthetic Biology Platform for Engineering Metabolic Pathways in E. coli

Synthetic biology devices as tools for metabolic engineering:

Parts plus pipes: Synthetic biology approaches to metabolic engineering:

Martin, V. J. , Pitera, D. J. , Withers, S. T. , Newman, J. D. & Keasling, J. D. Engineering a mevalonate pathway in Escherichia coli for production of terpenoids. Nature Biotechnol. 21, 796–802 (2003

P.D. Karp, R. Caspi. A survey of metabolic databases emphasizing the MetaCyc family

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