User:Nathan H. Joh

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Contact Info

Nathan H. Joh (an artistic interpretation)

Nathan H. Joh
UCSF
555 Mission Bay Blvd. North Rm. 482
Box 3122
San Francisco, CA 94158, US

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I work in the DeGrado Lab at UCSF.

Education

• 2009, PhD, UCLA

Research interests

1. Biophysics
2. Structural Biology
3. Protein Design

Publications

1. Joh NH, Wang T, Bhate MP, Acharya R, Wu Y, Grabe M, Hong M, Grigoryan G, and DeGrado WF. De novo design of a transmembrane Zn²⁺-transporting four-helix bundle. Science. 2014 Dec 19;346(6216):1520-4. DOI:10.1126/science.1261172 |
2. Schlebach JP, Kim MS, Joh NH, Bowie JU, and Park C. Probing membrane protein unfolding with pulse proteolysis. J Mol Biol. 2011 Mar 4;406(4):545-51. DOI:10.1016/j.jmb.2010.12.018 |
3. Oberai A, Joh NH, Pettit FK, and Bowie JU. Structural imperatives impose diverse evolutionary constraints on helical membrane proteins. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17747-50. DOI:10.1073/pnas.0906390106 |
4. Joh NH, Oberai A, Yang D, Whitelegge JP, and Bowie JU. Similar energetic contributions of packing in the core of membrane and water-soluble proteins. J Am Chem Soc. 2009 Aug 12;131(31):10846-7. DOI:10.1021/ja904711k |
5. Hong H, Joh NH, Bowie JU, and Tamm LK. Methods for measuring the thermodynamic stability of membrane proteins. Methods Enzymol. 2009;455:213-36. DOI:10.1016/S0076-6879(08)04208-0 |
6. Joh NH, Min A, Faham S, Whitelegge JP, Yang D, Woods VL, and Bowie JU. Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins. Nature. 2008 Jun 26;453(7199):1266-70. DOI:10.1038/nature06977 |

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