User:Nidharshan Anandasivam
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Contact Info
- Nidharshan Anandasivam
- MIT
- 229 Vassar St.
- Cambridge, MA 02139
- Email: dharshan{at}mit{dot}edu
- Email me through OpenWetWare
I work in the Bhatia Lab at MIT.
Education
MIT Biological Engineering (BSE) Class of 2014
Research interests
- Tissue Engineering Approaches to Cancer Research
- Rational Drug Design and Development
- Metabolism
Useful links
Registration/Questionnaire: 20.109 Spring 2012
Last Name
Anandasivam
First Name
Nidharshan
Preferred name/nickname (if not first)
Dharshan
Major/Minor
Biological Engineering Major Chemistry Minor
Year of Graduation
2014
Telephone #
9562991536
dharshan{at}mit{dot}edu
Preferred OH Time
After 5pm on Weekdays
Potentially Relevant Background
| Have you taken/are you taking... | Answer yes/no/when |
| 7.05/5.07 (Biochemistry) | Taken |
| 7.06 (Cell Biology) | Taking |
| 7.03 (Genetics) | Taken |
| 5.310 (General Chemistry Lab) | Not Taken |
| Do you have experience with... | Answer yes/no/type |
| Cell culture (microbial/mammalian/yeast?) | Yes, Mammalian |
| Molecular biology (electrophoresis, PCR, etc) | Yes |
Please briefly describe any previous laboratory experience
- Effect of d-catenin on VE-cadherin and N-cadherin in Endothelial Cells (National Cancer Institute, National Institutes of Health)
Determined effects of overexpression and knockdown of d-catenin on the cadherins. Bioinformatics Project: Used the NCBI database and Python programming to compare human and mouse amino acid sequences for various proteins associated with inflammation and cancer.
- Maintenance of Hepatocyte Phenotype in Tissue-Engineered Models (Harvard-MIT Division of Health Sciences and Technology)
Investigated effects of certain drugs on maintenance of the phenotype (measured using albumin secretion levels) of in vitro cultured hepatocytes.
- Cancer Genetics Research (Massachusetts General Hospital)
Conducted Fluorescent in situ Hybridization (FISH) on a genetically abnormal oligodendroglioma to confirm microarray results that detected amplification of certain genes on chromosome 7.
- Cancer Genetics Research (Boston University Medical Campus)
Investigated four cancer genes to determine response to histone deacetylase and Azidothymidine drug treatments. Investigated gene methylation of Smad7 expressed cell lines in comparison to that of normal cell lines.
Anything else you would like us to know?
I look forward to exploring the principles of RNA, protein, and cellular engineering.
Commitment to academic integrity
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