User:Steven J. Koch/MTC/April 5 2011

• Kramers' summary
  • A, B, C Diagram (Hanggi)
  • Particle sources, sinks, highly overdamped
  • Time scales
  • Continuity equation
  • Fick's 1st law
  • Smoluchowski equation
  • Markov process
  • Mean first passage time
  • Quiz -- in single-molecule force experiments, when does this model break down?
    • Biotin-streptavidin MD
  • Two applications--Larry's paper

• Efficient application of force
  • 2x2 matrix
  • Mag force old stuff
  • Halvorsen, Wong