User:TheLarry/Notebook/Larrys Notebook/2009/08/01
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2nd iterationI haven't edited this thing for a while but i might as well update what is going on. I am trying to make a kinetic monte carlo simulation of kinesin walking. For this i'll need to know rate constants and states for this process. I have read a shit load to find rate constants, and i should rummage through the papers and make a table of the many diff't constants. Later For now i am gonna write down what I think the states are: Let's start with nomenclature i've been using. i.e. F1-ATP-f | F2-ADP-b So let's pick a state to start in:
I need to add in the ability for a foot to unbind from the MT and rebind at the same spot--so not diffusing. I wonder if there is anything else i missed. I read some shit about a pause too. If that really is a state i would have missed that too. Questions
Rate Constantsso right now i have an arrow to and from each of these states except the detachment where it is only a one way street. also i know that some rate constants are load (force) dependant, but i am gonna ignore this for now. ok right now the table is in google docs but i'll embed it here soon |