User:Yiannis Kaznessis

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Contact Info

  • Yiannis Kaznessis
  • Department of Chemical Engineering and Materials Science
  • University of Minnesota
  • 421 Washington Ave SE
  • Minneapolis, MN 55455, USA
  • Email me through OpenWetWare

In my group we are interested in computational synthetic biology. We are developing the Synthetic Biology Software Suite, a publicly available software suite that assists in rationally designing synthetic gene regulatory networks. We combine components from BioBricks to generate networks of biomolecular reactions. We combine stochastic-discrete, stochastic-continuous and continuous-deterministic models to simulate these reaction networks. Version 1.0.2 is available on Sourceforge.net [1]. We are now incorporating the connection with BioBricks.

In recent work (Ramalingam, KI, Tomshine, JR, Maynard, JA, Kaznessis YN. " Forward engineering of synthetic bio-logical AND gates" Biochemical Engineering Journal, 2009, 47(1-3):38-47), we used multiscale models of gene regulatory networks to design, build and test bio-logical AND gates.

We are also participating in the iGEM competition. We were awarded a Gold Medal in 2009 for SynBioSS work.

Education

  • 1999, PhD, University of Notre Dame
  • 1994, BS, Aristotle University in Thessaloniki

Research interests

  1. Statistical mechanics (yes, it can be fun!)
  2. Synthetic biology
  3. Computer simulations

Computational Synthetic Biology Publications

Error fetching PMID 19830714:
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  1. Error fetching PMID 19830714: [Paper10]
  2. Error fetching PMID 19644174: [Paper11]
  3. Error fetching PMID 18757873: [Paper12]
  4. Error fetching PMID 17986347: [Paper1]
  5. Error fetching PMID 18190181: [Paper2]
  6. Error fetching PMID 17408514: [Paper3]
  7. Error fetching PMID 17200605: [Paper4]
  8. Error fetching PMID 16920827: [Paper5]
  9. Error fetching PMID 16504125: [Paper6]
  10. Error fetching PMID 16356038: [Paper7]
  11. Error fetching PMID 15740306: [Paper8]
  12. Error fetching PMID 16183880: [Paper9]
All Medline abstracts: PubMed HubMed

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