IGEM:IMPERIAL/2006/project/Oscillator/project browser/Predator Construct: Difference between revisions

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*This part is supposed to interface with the [[IGEM:IMPERIAL/2006/project/Oscillator/project_browser/Prey_Construct|'''prey-construct''']].
*This part is supposed to interface with the [[IGEM:IMPERIAL/2006/project/Oscillator/project_browser/Prey_Construct|'''prey-construct''']].
*To satify the Lotka-Volterra dynamic of the predator, this part has to fullfil two properties:
*To satify the Lotka-Volterra dynamic of the predator, this part has to fullfil two properties:
**'''promote the expression of the predator-molecule''' according to the prey and predator population.
**'''promote the growth of the predator-molecule''' according to the prey and predator population.
**'''degrade the prey-molecule''' according to the population of prey and predator
**'''kill the prey-molecule''' according to the population of prey and predator
*add links to other parts if necessary or other part of the wiki.
**enable the natural '''death of the predator-molecule'''


==Part interface==
==Part interface==
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! style="background:#66CC99"| INPUTS !!style="background:#FF3333"| OUTPUTS  
! style="background:#66CC99"| INPUTS !!style="background:#FF3333"| OUTPUTS  
|-
|-
|rowspan = "2" | Prey  || Predator growth  
| Prey  || Predator growth  
|-
|-
| Prey killing
|rowspan = "2" | Predator  || Prey killing
|-
| Predator death
|}
|}
||
||
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(try to write your specifications in tables. Here are just 2 examples)
(try to write your specifications in tables. Here are just 2 examples)
{| border="1" width="100%"
{| border="1" width="100%"
Interface specifiactions
Interface specifications
|-  
|-  
! style="background:lightgrey"|Characteristics !! Prey !! Predator expression !! Predator Killing  
! style="background:lightgrey"|Characteristics !! Prey !! Predator !! Predator expression !! Predator Killing  
|-
|-
| Range || Sensitivity to the prey should at least match the dynamic range of the prey || To be characterized || To be characterized
| Range || Sensitivity to the prey should at least match the dynamic range of the prey || Sensitivity to the predator should at least match the dynamic range of the predator || To be characterized || To be characterized
|-
|-
| Transfer function ||  n/a  || [[Image:IGEM_IMPERIAL_TransferFunctionPredator1.png|250px]]  ||  [[Image:IGEM_IMPERIAL_TransferFunctionPredator2.png|250px]]  
| Transfer function ||  n/a  || n/a || [[Image:IGEM_IMPERIAL_TransferFunctionPredator1.png|250px]]  ||  [[Image:IGEM_IMPERIAL_TransferFunctionPredator2.png|250px]]  
|-
|-
| Variability||  n/a    || population level + day-to-day variability low  ||  population level + day-to-day variability low     
| Variability||  n/a    || n/a    || population level + day-to-day variability low  ||  population level + day-to-day variability low     
|}
|}


Revision as of 09:58, 19 October 2006

Super Parts Molecular Prey-Predator Oscillator
Actual Part Logo of the Part
Sub Parts Test Sensing Predator Construct Test Killing Predator Construct


Motivations

  • This part is driving the molecular events associated with the predator in the Lotka-Volterra model.
  • This part is supposed to interface with the prey-construct.
  • To satify the Lotka-Volterra dynamic of the predator, this part has to fullfil two properties:
    • promote the growth of the predator-molecule according to the prey and predator population.
    • kill the prey-molecule according to the population of prey and predator
    • enable the natural death of the predator-molecule

Part interface

INPUTS OUTPUTS
Prey Predator growth
Predator Prey killing
Predator death

Expected behavior and performances

(try to write your specifications in tables. Here are just 2 examples)

Interface specifications
Characteristics Prey Predator Predator expression Predator Killing
Range Sensitivity to the prey should at least match the dynamic range of the prey Sensitivity to the predator should at least match the dynamic range of the predator To be characterized To be characterized
Transfer function n/a n/a
Variability n/a n/a population level + day-to-day variability low population level + day-to-day variability low


System level specifications
Properties Comments
Range
Transfer function
Latency
Robustness
Variability
properties 3
properties 4

Open issues

  • Getting linear relationship is going to be challenging in a biological system.
  • Saturation in the response may have to be taken into account (characterized and defined).
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