User:Liuzhec
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Project Overview
- Our goal is to design and implement molecular containers, which can be dynamically opened and closed by an external stimulus.
- The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility.
- As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers.
- We expect that molecular containers could have several interesting scientific and clinical applications, such as
- Drug and gene delivery
- Bio-marker scavenging (early detection of biomarkers)
- Directed evolution (compartmentalized selections)
- Using multiplexing for combinatorial chemical synthesis
- Capture and stabilization of multiprotein complexes
- Protein folding (chaperones)
- Cell sorting
==Working Team Members== edit
- Tiffany Chan (talk, edits)
- Katherine Fifer (talk, edits)
- Valerie Lau (talk, edits)
- Matthew Meisel (talk, edits)
- Lewis Hahn (talk, edits)
- TA: Shawn Douglas (talk, edits)
Recent Changes
List of abbreviations:
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4 May 2024
| 18:10 | The Paper that Launched Microfluidics - Xi Ning diffhist −86 Xning098 talk contribs (→Electrokinetic effect) | ||||
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09:20 | User:Massih Forootan 3 changes history +83 [Massih Forootan (3×)] | |||
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07:28 | CHEM-ENG590E:Wiki Textbook 4 changes history −445 [Sarah L. Perry (4×)] | |||
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| 07:18 | Move log Sarah L. Perry talk contribs moved page Microfluidic Gradient Generators - Greg Schneider to Microfluidic Gradient Generators (Adding an Author) | ||||
| 00:15 | Renhao Li Lab:Publications diffhist +265 Renhao Li talk contribs (→2024) | ||||
3 May 2024
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14:33 | UA Biophysics:Protocols:Kanamycin 5 changes history −421 [Elizabeth Suesca (5×)] | |||
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14:29 | UA Biophysics:Protocols:Chloramphenicol 2 changes history −427 [Elizabeth Suesca (2×)] | |||
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N 12:09 | BioMicroCenter:Oligo Synthesis 7 changes history +4,408 [Noelani Kamelamela (7×)] | |||
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08:16 (cur | prev) +4,383 Noelani Kamelamela talk contribs (Created page with "{{BioMicroCenter}} ''' ** All users must be trained before being allowed to use the equipment **'''<BR><BR> The BioMicro Center currently hosts two oligo synthesizers: one Dr Oligo 96 (Biolytic) and one Syntax STX-200 (DNAScript). <br><br> Dr Oligo is optimized for higher concentrations of oligos made through polyamidite synthesis. For ready to use oligos a series of steps must be completed using the other related machines in the Center including the column presser, the...") | |||
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12:06 | BioMicroCenter:Covaris 5 changes history +172 [Noelani Kamelamela (5×)] | |||
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08:28 Noelani Kamelamela talk contribs uploaded File:DrOligo.jpg | ||||
2 May 2024
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19:54 | Paper Microfluidic Device for Archiving Breast Epithelial Cells 5 changes history −389 [Xning098 (5×)] | |||
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Back row (L-R): Lewis, Katie, Tiffany, Valerie, Zhipeng, Matt.
Front row (L-R): Hetmann, Jeffrey, David, Perry.
And yes, that is the back end of a bronze rhinoceros.
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A thanks goes to MIT's team page for our page formatting.
