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WIKIPEDIA BIO154/254: Molecular and Cellular Neurobiology

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Frequently Asked Questions:

1. What is forward genetics? Reverse genetics?
2. What are the roles of Robo, Slit, and Commissureless in axon guidance?
Where are these proteins expressed?
3. How does Commissureless keep Robo in the Golgi? How is Robo expression regulated?
4. What are the results of overexpressing the different Robo proteins?
5. Why would one Dscam isoform repel the same isoform?
6. How is a gradient established?
7. What is an ocular dominance column?
8. What is a retina wave? What role does it play in the formation of ocular dominance columns?

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